Detalhe da pesquisa
1.
Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells.
Blood
; 2024 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38493479
2.
On- and off-target effects of paired CRISPR-Cas nickase in primary human cells.
Mol Ther
; 32(5): 1298-1310, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38459694
3.
CRISPR-Cas9n-mediated ELANE promoter editing for gene therapy of severe congenital neutropenia.
Mol Ther
; 2024 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38556793
4.
A novel Cas9 fusion protein promotes targeted genome editing with reduced mutational burden in primary human cells.
Nucleic Acids Res
; 51(9): 4660-4673, 2023 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37070192
5.
Gene editing of hematopoietic stem cells restores T-cell response in familial hemophagocytic lymphohistiocytosis.
J Allergy Clin Immunol
; 153(1): 243-255.e14, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37595758
6.
CRISPR-Cas12a for Highly Efficient and Marker-Free Targeted Integration in Human Pluripotent Stem Cells.
Int J Mol Sci
; 25(2)2024 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38256061
7.
Immunopathology caused by impaired CD8+ T-cell responses.
Eur J Immunol
; 52(9): 1390-1395, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35099807
8.
Hypoxia enhances anti-fibrotic properties of extracellular vesicles derived from hiPSCs via the miR302b-3p/TGFß/SMAD2 axis.
BMC Med
; 21(1): 412, 2023 10 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37904135
9.
Prediction and validation of hematopoietic stem and progenitor cell off-target editing in transplanted rhesus macaques.
Mol Ther
; 30(1): 209-222, 2022 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34174439
10.
Paired nicking-mediated COL17A1 reframing for junctional epidermolysis bullosa.
Mol Ther
; 30(8): 2680-2692, 2022 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35490295
11.
Targeted multi-epitope switching enables straightforward positive/negative selection of CAR T cells.
Gene Ther
; 28(9): 602-612, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33526841
12.
Assessing the differential impact of chronic CMV and treated HIV infection on CD8+ T-cell differentiation in a matched cohort study: is CMV the key?
AIDS Res Ther
; 18(1): 37, 2021 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34193181
13.
Biodegradable Nanocarriers Resembling Extracellular Vesicles Deliver Genetic Material with the Highest Efficiency to Various Cell Types.
Small
; 16(3): e1904880, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31840408
14.
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells.
Nucleic Acids Res
; 46(9): 4456-4468, 2018 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29538770
15.
Chimerization Enables Gene Synthesis and Lentiviral Delivery of Customizable TALE-Based Effectors.
Int J Mol Sci
; 21(3)2020 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31991825
16.
Targeted Integration of Inducible Caspase-9 in Human iPSCs Allows Efficient in vitro Clearance of iPSCs and iPSC-Macrophages.
Int J Mol Sci
; 21(7)2020 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32260086
17.
Inhibition of replication of hepatitis B virus using transcriptional repressors that target the viral DNA.
BMC Infect Dis
; 19(1): 802, 2019 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31510934
18.
Rescue of DNA-PK Signaling and T-Cell Differentiation by Targeted Genome Editing in a prkdc Deficient iPSC Disease Model.
PLoS Genet
; 11(5): e1005239, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26000857
19.
Adenoviral vector DNA for accurate genome editing with engineered nucleases.
Nat Methods
; 11(10): 1051-7, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25152084
20.
Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome.
Mol Ther
; 24(3): 636-44, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26658966